Figure 1. In vivo analysis of sarcolemmal membrane integrity after burn injury in mice.
(a) EBD was intramuscularly injected into control and burn injured (Post Burn Day 14) mice. Membrane-injured myofibers in gastrocnemius muscles from sham injury (C) and burn injury (B) in mice are labeled. The number of EBD-positive myofibers counted from these micrographs. *P < 0.05; vs. Control; n = 5. (Scale bar, 500 μm; 200 μm). (b) EBD was intraperitoneally injected into control and burn injured (Post Burn Day14) mice. Membrane-injured myofibers in gastrocnemius muscles from sham injury (C) and burn injury (B) in mice are labeled. The number of EBD-positive myofibers counted from these micrographs. *P < 0.05; vs. Control; n = 5 (Scale bar, 500 μm; 200 μm).