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. 2016 Aug 22;6:31656. doi: 10.1038/srep31656

Figure 3. Thymoquinone (TQ) decreased the expression of COX-2 induced by high glucose and lipopolysaccharide (LPS).

Figure 3

(A,B) RSC96 cells were induced by 100mM glucose for 24 h, then cells were treated with 5, 20, or 80 μM TQ and 10 μM NS-398 for 24 h. (A) A representative western blot of COX-2 is shown. HG: high glucose. (B) The relative density of COX-2 expression. **p < 0.01 versus the normal group; #p < 0.05 versus the control group, ##p < 0.01 versus the control group. (C,D) RSC96 cells were induced by 1 μg/L LPS and treated with 20 μM TQ for 24 h. (C) A representative western blot of COX-2 is shown. (B) The relative density of COX-2 expression. **p < 0.01 versus the normal group; ##p < 0.01 versus the control group.