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. 2016 Aug 22;6:31656. doi: 10.1038/srep31656

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A) Normal group; (B) T2DMgroup; (C) DPN group; (D) DPN+TQ5 group; (E) DPN+TQ2 group; (F) DPN+VitB12 group. T2DM: type 2 diabetes mellitus; TQ2: 2 mg/kg TQ; TQ5: 5 mg/kg TQ; VitB12: vitamin B12; m: myelin, a: axon. Panel shows longitudinal sections with 3000X amplification (scale bar = 5 μm).