Table 2. Thymoquinone (TQ) reduced inflammatory factor expression in plasma of diabetic peripheral neuropathy (DPN) rats.
| Time | IL-6 | IL-1β |
|---|---|---|
| Normal group | OOR< | OOR< |
| T2DM group | 9.937 + 1.406 | 376.8 + 57.96 |
| DPN group | 10.845 + 1.15 | 384 + 34.44 |
| DPN+TQ5 group | OOR<** | 129.3 + 48.11** |
| DPN+TQ2 group | OOR<** | 305.3 + 57.1 |
| DPN+VitB12 group | OOR<** | 366.3 + 72.58 |
Note: 6 weeks after TQ administration, IL-6 and IL-1β expression were detected by Bio-Plex ProTM Assays. OOR<”means much smaller than the minimum detection range. **p < 0.01 versus the DPN group. T2DM: type 2 diabetes mellitus; TQ2: 2 mg/kg TQ; TQ5: 5 mg/kg TQ; VitB12: vitamin B12. Unit of inflammatory factors: pg/ml.