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. 2016 Aug 22;6:31540. doi: 10.1038/srep31540

Figure 2. SV accumulation in the Caps1 cKO presynapse.

Figure 2

(A) Representative images of presynaptic boutons in the CA3–CA1 stratum radiatum in control and Caps1 cKO mice. The presynaptic bouton is coloured in purple (scale bar: 200 nm). (B) Number of SVs in control and Caps1 cKO synapses; n = 48 and 51 synapses for control and Caps1 cKO, respectively. ***P < 0.001, Student’s t-test. (C) The area of the presynapse in control and Caps1 cKO synapses; n = 48 and 51 synapses for control and Caps1 cKO, respectively. P = 0.14, Student’s t-test. (D) Cumulative frequency of active zone length in control and Caps1 cKO synapses; n = 49 and 88 active zones for control and Caps1 cKO, respectively. P = 0.33, Kolmogorov–Smirnov test. (E) Cumulative frequency of PSD length in control and Caps1 cKO synapses; n = 49 and 86 PSDs for control and Caps1 cKO, respectively. P = 0.61, Kolmogorov–Smirnov test.