Table 1.

Demographic Characteristics of Subjects with Depression and Normal Control Subjects

		Age (years)	Race	Gender	PMI (hours)	Brain pH	Cause of Death	Psychotropic drugs (at the time of death)	Psychiatric Diagnosis
Normal Control Subjects a
1	CONTROL	22	Black	Male	19	6.9	GSW	None	Normal
2	CONTROL	42	White	Female	23	7.2	Pneumonia	None	Normal
3	CONTROL	37	Black	Male	5	7.1	ASCVD	None	Normal
4	CONTROL	31	Black	Male	8	7.2	GSW	None	Normal
5	CONTROL	46	Black	Male	9	7.1	Multiple injuries	None	Normal
6	CONTROL	33	White	Male	15	7.0	GSW	None	Normal
7	CONTROL	48	White	Male	26	6.9	ASCVD	None	Normal
8	CONTROL	40	White	Female	7	7.0	ASCVD	None	Normal
9	CONTROL	23	Black	Male	15	6.8	GSW	None	Normal
10	CONTROL	38	Black	Male	16	6.9	Lung Sarcoidosis	None	Normal
11	CONTROL	65	Black	Female	23	6.9	ASCVD	None	Normal
12	CONTROL	52	White	Male	30	7.3	ASCVD	None	Normal
13	CONTROL	35	White	Male	24	6.9	Crush injury to abdomen and chest	None	Normal
14	CONTROL	37	White	Male	24	7.0	ASCVD	None	Normal
15	CONTROL	45	White	Male	22	7.3	ASCVD	None	Normal
16	CONTROL	26	White	Male	12	6.9	Arrhythmia	None	Normal
17	CONTROL	72	White	Female	23	6.9	MVA	None	Normal
18	CONTROL	42	White	Female	23	6.9	Mitral valve prolapse	None	Normal
19	CONTROL	47	White	Male	10	7.0	ASCVD	None	Normal
20	CONTROL	31	White	Male	16	7.2	MVA	None	Normal
21	CONTROL	60	White	Male	15	7.1	Accidental drowning	None	Normal
22	CONTROL	28	White	Male	13	6.8	Electrocution	None	Normal
23	CONTROL	45	White	Female	16	6.9	Cardiac arrhythmia	None	Normal
24	CONTROL	62	White	Male	19	7.0	Cardiac arrest	None	Normal
Depressed Subjects b
1	SUICIDE	27	White	Male	24	7.0	GSW	None	MDD, Ethanol abuse
2	SUICIDE	44	White	Female	11	7.2	Drug OD	Nortriptyline	MDD, Ethanol abuse
3	SUICIDE	36	White	Female	10	7.1	GSW	None	MDD
4	SUICIDE	24	White	Male	7	7.1	GSW	Ethanol	MDD
5	SUICIDE	43	White	Male	12	7.0	Drug OD	None	MDD, Polysubstance Abuse
6	SUICIDE	53	White	Male	23	6.9	Jump from height	None	MDD
7	SUICIDE	41	White	Female	27	7.1	Drug OD	Amitriptyline, Desipramine, Nortriptyline, Ethanol	MDD, Ethanol abuse
8	SUICIDE	22	Black	Female	16	7.3	Drug OD	None	MDD
9	SUICIDE	46	White	Female	21	6.9	Drug OD	Amitriptyline, Desipramine, Ethanol	MDD
10	SUICIDE	36	White	Female	18	7.2	GSW	None	MDD
11	SUICIDE	38	White	Male	24	7.0	Drug OD, Ethanol intoxication	Ethanol	MDD, Ethanol abuse
12	SUICIDE	46	White	Female	16	6.8	Drug OD	Nortriptyline	MDD, Panic disorder with agoraphobia
13	SUICIDE	23	White	Male	12	7.0	Hanging	Paroxetine	MDD
14	SUICIDE	30	White	Male	17	7.1	Hanging	Venlafaxine	MDD
15	SUICIDE	44	White	Female	30	7.2	Drug OD, Ethanol intoxication	Fluoxetine, Ethanol	MDD, Ethanol abuse, Opioid abuse
16	SUICIDE	74	White	Female	27	7.0	Venlafaxine OD	Venlafaxine, Ethanol	MDD, Ethanol abuse
17	SUICIDE	25	White	Male	14	6.8	Hanging	Ethanol	MDD
18	SUICIDE	23	Black	Male	23	6.9	Hanging	None	MDD
19	SUICIDE	63	White	Male	19	6.9	Drug OD, Ethanol intoxication	Ethanol	MDD
20	SUICIDE	67	White	Male	22	7.0	GSW	Fluoxetine, Venlafaxine	MDD
21	SUICIDE	40	White	Female	20	7.0	Drug OD	Xanax	MDD
22	SUICIDE	53	White	Male	26	7.1	Stabbing	Sertraline	MDD
23	SUICIDE	68	White	Female	26	6.8	GSW	Amitriptyline	Bipolar Disorder
24	SUICIDE	31	White	Female	31	6.8	Hanging	Trazadone, Ethanol	Bipolar Disorder, Bulimia, OCD
25	SUICIDE	51	White	Female	28	6.9	Amitriptyline OD	Amitriptyline, Ethanol	Bipolar Disorder, Ethanol abuse

Abbreviations: ASCVD, atherosclerotic cardiovascular disease; CO, carbon monoxide; DKA, diabetic ketoacidosis; GSW, gunshot wound; MDD, major depressive disorder; MVA, motor vehicle accident; OCD, obsessive-compulsive disorder; OD, overdose; PMI, postmortem interval

^aMean ± SD age is 41.96 ± 13.19 years; PMI, 17.21 ± 6.65 h; and brain pH 7.01 ± 0.15

^bMean ± SD age is 41.92 ± 15.07 years; PMI, 20.16 ± 6.68 h; and brain pH 7.00 ± 0.14