Table 2.

HRs for over-all and cause-specific cancer incidence by ABO blood type.

Cancer site	Blood type	N	Incidence rate (per 100,000 person-years)	HRa (95% CI)	HRb (95% CI)
Overall	O	3921	339.86	1.00 (Reference)	1.00 (Reference)
	A	2560	353.28	1.02 (0.97–1.07)	1.04 (0.98–1.10)
	B	2171	329.56	0.94 (0.89–0.99)	0.97 (0.91–1.02)
	AB	512	316.37	0.92 (0.84–1.01)	0.90 (0.81–1.00)
	Non-O	5243	339.30	0.97 (0.93–1.02)	0.99 (0.95–1.04)
Oral	O	262	22.71	1.00 (Reference)	1.00 (Reference)
	A	180	24.84	1.08 (0.89–1.30)	1.06 (0.86–1.30)
	B	147	22.31	0.96 (0.78–1.17)	0.97 (0.77–1.21)
	AB	38	23.48	1.03 (0.73–1.44)	0.93 (0.62–1.37)
	Non-O	365	23.62	1.02 (0.87–1.20)	1.01 (0.84–1.20)
Esophagus	O	52	4.51	1.00 (Reference)	1.00 (Reference)
	A	33	4.55	0.95 (0.61–1.48)	1.08 (0.67–1.74)
	B	27	4.10	0.85 (0.53–1.36)	0.96 (0.58–1.60)
	AB	8	4.94	1.08 (0.51–2.28)	1.01 (0.43–2.39)
	Non-O	68	4.40	0.92 (0.64–1.33)	1.02 (0.69–1.53)
Lung	O	429	37.18	1.00 (Reference)	1.00 (Reference)
	A	294	40.57	1.05 (0.91–1.22)	1.01 (0.85–1.19)
	B	281	42.66	1.08 (0.93–1.26)	1.08 (0.92–1.28)
	AB	61	37.69	0.97 (0.74–1.28)	1.03 (0.77–1.38)
	Non-O	636	41.16	1.06 (0.94–1.20)	1.04 (0.91–1.19)
Stomach	O	215	18.64	1.00 (Reference)	1.00 (Reference)
	A	180	24.84	1.28 (1.05–1.56)	1.38 (1.11–1.72)
	B	104	15.79	0.81 (0.64–1.03)	0.82 (0.63–1.07)
	AB	25	15.45	0.81 (0.54–1.23)	0.92 (0.59–1.44)
	Non-O	309	20.00	1.03 (0.87–1.23)	1.09 (0.90–1.33)
Liverc	O	625	54.17	1.00 (Reference)	1.00 (Reference)
	A	361	49.82	0.89 (0.79–1.02)	0.92 (0.80–1.07)
	B	339	51.46	0.92 (0.81–1.05)	0.96 (0.83–1.12)
	AB	69	42.64	0.77 (0.60–0.99)	0.81 (0.61–1.07)
	Non-O	769	49.77	0.89 (0.80–0.99)	0.93 (0.82–1.04)
Pancreas	O	51	4.42	1.00 (Reference)	1.00 (Reference)
	A	50	6.90	1.50 (1.02–2.22)	1.45 (0.94–2.26)
	B	45	6.83	1.47 (0.99–2.20)	1.59 (1.02–2.48)
	AB	10	6.18	1.36 (0.69–2.68)	1.37 (0.64–2.93)
	Non-O	105	6.80	1.48 (1.06–2.06)	1.50 (1.04–2.19)
Rectum	O	205	17.77	1.00 (Reference)	1.00 (Reference)
	A	159	21.94	1.20 (0.97–1.47)	1.19 (0.94–1.51)
	B	126	19.13	1.04 (0.83–1.30)	1.09 (0.85–1.40)
	AB	28	17.30	0.96 (0.65–1.42)	1.00 (0.65–1.55)
	Non-O	313	20.26	1.10 (0.93–1.32)	1.13 (0.93–1.38)
Colon	O	328	28.43	1.00 (Reference)	1.00 (Reference)
	A	226	31.19	1.06 (0.90–1.26)	1.12 (0.93–1.36)
	B	172	26.11	0.89 (0.74–1.07)	0.96 (0.78–1.17)
	AB	46	28.42	0.98 (0.72–1.34)	1.01 (0.71–1.42)
	Non-O	444	28.73	0.98 (0.85–1.13)	1.04 (0.89–1.22)
Kidney	O	125	10.83	1.00 (Reference)	1.00 (Reference)
	A	64	8.83	0.79 (0.58–1.07)	0.82 (0.58–1.14)
	B	58	8.80	0.78 (0.57–1.06)	0.72 (0.50–1.03)
	AB	12	7.42	0.67 (0.37–1.21)	0.41 (0.18–0.93)
	Non-O	134	8.67	0.77 (0.61–0.99)	0.73 (0.56–0.96)
Bladder	O	85	7.37	1.00 (Reference)	1.00 (Reference)
	A	68	9.38	1.21 (0.88–1.67)	1.11 (0.75–1.63)
	B	66	10.02	1.28 (0.93–1.77)	1.32 (0.91–1.93)
	AB	17	10.50	1.38 (0.82–2.32)	1.58 (0.88–2.82)
	Non-O	151	9.77	1.26 (0.97–1.64)	1.25 (0.91–1.71)
Leukemia	O	67	5.81	1.00 (Reference)	1.00 (Reference)
	A	38	5.24	0.89 (0.60–1.32)	0.86 (0.55–1.34)
	B	35	5.31	0.89 (0.59–1.35)	0.97 (0.63–1.51)
	AB	6	3.71	0.63 (0.27–1.46)	0.64 (0.25–1.59)
	Non-O	79	5.11	0.86 (0.62–1.20)	0.89 (0.62–1.27)
Breast (female)	O	506	81.33	1.00 (Reference)	1.00 (Reference)
	A	300	77.39	0.95 (0.82–1.09)	0.95 (0.82–1.12)
	B	271	77.31	0.94 (0.81–1.09)	0.92 (0.78–1.09)
	AB	70	80.21	0.99 (0.77–1.27)	0.87 (0.65–1.17)
	Non-O	641	77.65	0.95 (0.84–1.07)	0.93 (0.82–1.06)
Prostate (male)	O	223	41.95	1.00 (Reference)	1.00 (Reference)
	A	165	48.96	1.08 (0.88–1.32)	1.22 (0.98–1.53)
	B	122	39.58	0.87 (0.70–1.09)	0.95 (0.74–1.22)
	AB	32	42.92	0.95 (0.66–1.38)	0.89 (0.58–1.38)
	Non-O	319	44.32	0.98 (0.82–1.16)	1.07 (0.88–1.30)

^aAdjusted for age and sex.

^bAdjusted for age, sex, education level, smoking status, alcohol drinking status, physical activity, and BMI. Individuals with missing covariates were excluded from each model.

^cAlso adjusted for HBV infection.