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. Author manuscript; available in PMC: 2016 Aug 22.
Published in final edited form as: Lancet Oncol. 2016 Jun 6;17(7):984–993. doi: 10.1016/S1470-2045(16)30146-2

Table 1.

Baseline demographics and disease history in ≥ second-line patients

N=57

Age, median (range), years 64 (41–88)

Sex, n (%)
 Male 29 (51)
 Female 28 (49)

Race, n (%)
 White 49 (86)
 Black 2 (4)
 Asian 4 (7)
 Mixed 1 (2)
 Missing 1 (2)

ECOG performance status, n (%)
 0 17 (30)
 1 35 (61)
 2 5 (9)

Histology at initial diagnosis, n (%)
 Adenocarcinoma* 56 (98)
 Large cell 1 (2)

History of tobacco use, n (%)
 Never smoker 16 (28)
 Current smoker 6 (11)
 Former smoker 35 (61)

Smoking history, n (%) n = 41
 ≤30 pack-years 22 (54)
 >30 pack-years 19 (46)

Number of prior systemic regimens for metastatic disease, n (%)
 1 38 (67)
 ≥2 19 (33)
*

Includes 1 patient with adenosquamous carcinoma—predominately adenocarcinoma histology—and 2 patients with lepidic predominant or invasive mucinous adenocarcinoma (formerly known as bronchioalveolar carcinoma). All histology was determined by local pathological report.