Adverse effects of colorectal cancer screening (14) |
Fear and anxiety related to colonoscopy |
Potentially lower uptake of colorectal cancer screening. Potentially higher rates of undiagnosed cancer and worse morbidity and mortality (i.e., worse individual and population outcomes) |
Use of HbA1c increases rates of diabetes screening for at-risk adolescents in primary care settings (15) |
Use of non-fasting blood test rather than the need for fasting samples |
Increased screening rates for diabetes. (i.e., improved individual and population outcomes) Lower accuracy of results than oral glucose tolerance tests (i.e., negative impact on test results) |
Noninvasive measures of liver elasticity rather than liver biopsy to diagnose or screen for cirrhosis (17) |
Using non-invasive measures of liver elasticity causes less pain, discomfort and risks for the patient, is more rapid than liver biopsy, and is also less invasive. |
Fewer complications caused by liver biopsies, which occur in up to 5% of patients. (i.e., improved individual outcomes) |
Intraoperative frozen-section diagnosis of ovarian tumors (18) |
Intraoperative test results can improve surgical management and increase diagnostic accuracy of non-borderline ovarian tumors during surgery |
Obtaining immediate results will enable patient to receive prompt access to appropriate treatment, ideally improving patient outcomes and reducing mortality. (ie improved speed of getting test results and ability to act on results) |