| Use of specific EKG criteria to screen athletes for cardiomyopathy or risk of sudden cardiac death, compared to regular EKG criteria (19) |
Using a small subset of athlete-specific EKG parameters can improve the interpretability of EKG screening and reduce the frequency of diagnosing false positives |
Improved interpretability reduces false positive screening tests in athletes, and potentially Save resources, time, and patient distress and discomfort by eliminating unnecessary further tests and treatments of false positives (ie improved patient experience) |
| Suboptimal accuracy of screening mammography (20) |
Significant proportion of false positive mammograms in women undergoing screening |
Psychological harms persisted for 3 years in those with false positive tests (i.e., negative impact on test experience) |
| Improved accuracy of diagnosis of malaria in febrile patients (21) |
More accurate diagnosis of malaria, fewer false positives based on solely clinical diagnosis |
More appropriate treatment with antimalarials (i.e., improved patient management outcomes.) Possibly lower antimalarial resistance rates in future (i.e., population outcomes). Possible difficulty maintaining test supplies and cost of tests longer term (i.e., negative effects on test availability) |
| Diagnosis of acute pharyngitis without a confirmatory test after a negative rapid antigen detection test (RADT) result (22) |
Low diagnostic confidence in RADT tests can lead to overprescribing unnecessary antibiotics in patients |
Low diagnostic confidence in result, Increased antibacterial resistance among the population as well as unnecessary treatment costs for the patient and insurer; potential antibiotic side effects (ie |
