Table 4.

Odds ratios and 95% confidence intervals for association of angiotensin II type 1 receptor single nucleotide polymorphisms and hypertension under dominant, recessive and additive genetic models

rs#	Ethnicity	Reference	Autosomal dominant		Autosomal recessive		Additive
			OR	95% CI	OR	95% CI	OR	95% CI
rs188018	German	Zhang 2000	0.99	(0.71–1.39)			0.99	(0.95–1.04)
	Tibetan	Sun 2004	0.80	(0.5–1.28)	0.56	(0.35–0.89)	0.82	(0.75–0.9)
	Mongolian	Wang 2006	0.87	(0.59–1.29)	0.31	(0.21–0.45)	0.83	(0.78–0.89)
		Summary	0.91a	0.72–1.13			0.90b	0.73–1.10
			I2 = 0%				I2 = 0%
rs1880765	German	Zhang 2000	1.93	(1.01–3.67)			1.88	(1.53–2.31)
rs275650	Japanese	Takahashi 2000	1.44	(0.8–2.6)			1.23	(1.05–1.42)
rs275651	Japanese	Takahashi 2000	1.44	(0.8–2.6)			1.23	(1.05–1.42)
	Chinese	Jin 2003	1.58	(0.99–2.5)	1.77	(1.12–2.82)	1.54	(1.42–1.68)
rs275652	Japanese	Takahashi 2000	1.44	(0.8–2.6)			1.23	(1.05–1.42)
rs1492078	African American	Henderson 2004	2.56	(1.47–4.47)	1.13	(0.65–1.96)	1.23	(1.21–1.25)
	Hispanic American	Henderson 2004	0.98	(0.75–1.28)	1.31	(1–1.71)	1.03	(1.01–1.06)
	German	Zhang 2000	0.85	(0.62–1.18)	0.54	(0.39–0.75)	0.8	(0.78–0.82)
	Japanese	Takahashi 2000	1.86	(1.14–3.04)	1.27	(0.78–2.07)	1.63	(1.49–1.79)
	Chinese Han	Jin 2003	1.36	(0.92–2.03)	1.42	(0.96–2.12)	0.32	(1.25–1.4)
	Tibetan	Sun 2004	0.73	(0.47–1.15)	0.44	(0.28–0.69)	0.74	(0.69–0.81)
		Summary	Heterogeneity P = 0.001		Heterogeneity P = 0.08		Heterogeneity P = 0.005
			I2 = 76%		I2 = 49%		I2 = 70%
rs422858	Japanese	Takahashi 2000	1.46	(0.8–2.65)			1.34	(1.14–1.58)
rs275653	Japanese	Takahashi 2000	1.46	(0.8–2.65)			1.34	(1.14–1.58)
	Mongolian	Wang 2006	0.9	(0.63–1.3)	0.93	(0.64–1.34)	0.92	(0.87–0.97)
rs5182	French	Bonnardeaux 1994	1.3	(0.82–2.07)	0.99	(0.62–1.57)	1.08	(1.04–1.11)
rs5186		See Figures 1, A–C
rs380400	French	Bonnardeaux 1994	0.92	(0.61–1.39)	0.57	(0.38–0.87)	0.91	(0.84–0.97)

OR, odds ratio; CI, confidence interval.

^aHeterogeneity P = 0.76; Egger test P = 0.11.

^bHeterogeneity P = 0.69; Egger test P = 0.14.