Table 5. Additional adjusted two-slope models (Model 3) of leukocyte telomere length and age (N=1504).
| Models tested | |||||||
|---|---|---|---|---|---|---|---|
| Model | −2LL | Parms | AIC | BIC | Reference model | Δ-2LL | df |
| 3 | −1834.2 | 17 | −1802.2 | −1740.1 | -- | -- | -- |
| 3+slope2*sex | −1834.4 | 18 | −1800.4 | −1734.4 | 3 | 0.2 | 1 |
| 3+GRS | −1843.1 | 18 | −1809.1 | −1743.2 | 3 | 8.9 | 1** |
| 3+GRS+slope2*GRS | −1843.9 | 19 | −1807.9 | −1738.0 | 3+GRS | 0.8 | 1 |
| 3+GRS+sex*GRS | −1843.2 | 19 | −1807.2 | −1737.3 | 3+GRS | 0.1 | 1 |
Chi-square tests for deviance: **p-value<0.01; In all models, sex as covariate as well as random effects between twin pairs and between individuals were included. LL: log-likelihood. Parms: parameters; AIC: Akaike Information Criterion; BIC: Bayesian Information Criterion; df: degrees of freedom; GRS: Genetic Risk Score.