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. 2016 Aug 22;11(8):e0161342. doi: 10.1371/journal.pone.0161342

Table 2. Concentration of α1-antitrypsin, α2-macroglobulin, α1-acid glycoprotein and total protein concentration in the serum of women during each trimester of pregnancy.

Total protein
[g/l]
α1-antitrypsin
[mg/dl]
α1-acid glycoprotein
[μg/dl]
α2-macroglobulin
[g/l]
Transferrin
[g/l]
1st trimester S n = 6 80.16 ± 3.701 311.71 ± 40.45* 1143.02 ± 211.52 3.44 ± 0.44 3.34 ± 0.515
NS n = 18 79.66 ± 4.222 231.24 ± 97.17*,3 1078.69 ± 240.27 3.20 ± 0.574 3.67 ± 0.546
2nd trimester S n = 7 78.62 ± 4.54 289.56 ± 72.23 1139.35 ± 216.29 4.37 ± 1.14** 4.02 ± 0.24
NS n = 35 78.13 ± 5.83 290.38 ± 98.39 1058.62 ± 238.09 3.65 ± 0.94** 4.10 ± 0.597
3rd trimester S n = 10 74.49 ± 3.371 319.57 ± 95.83 1117.24 ± 212.69 3.56 ± 1.25 4.46 ±0.775
NS n = 31 76.05 ± 4.172 314.13 ± 110.403 1092.74 ± 202.57 3.81 ± 0.644 4.49 ± 0.626,7

Groups–S: smoking; NS: non-smoking.

*-** significant (p < 0.02) for the same parameter in the same trimester for different smoking groups (e.g. *S group in the 1st trimester has higher levels of α1-antitrypsin than NS group in the same trimester)

1–7 significant (p < 0.05) for the same parameter in the same group to the other trimester (e.g. 1S group in the 1st trimester has higher levels of total protein concentration than in the 3rd trimester)