Table 2. Maternal body weight, glucose tolerance, energy intake and plasma insulin and leptin concentrations during pregnancy and lactation.
NFD (n) | HFD (n) | P | ||
---|---|---|---|---|
Body weight (g) | E0.5 | 24.0 ± 0.4 (27) | 26.1 ± 0.3 (31) | 0.002 |
E15.5 | 34.6 ± 0.6 (8) | 37.8 ± 0.7 (8) | 0.002 | |
E18.5 | 41.1 ± 1.0 (7) | 40.3 ± 0.7 (10) | 0.61 | |
PN21 | 30.8 ± 0.8 (12) | 31.9 ± 0.8 (13) | 0.36 | |
Pregnancy weight gain (E0.5-E18.5) (g) | 16.5 ± 0.5 (7) | 14.0 ± 0.6 (10) | 0.006 | |
Glucose AUC (mmol/l.min) | E15.5 | 1663.1 ± 116.5 (8) | 1824.4 ± 74.9 (8) | 0.24 |
E18.5 | 1352.4 ± 76.2 (7) | 1482.9 ± 65.0 (10) | 0.21 | |
PN21 | 1227.5 ± 121.8 (12) | 1237.2 ± 104.5 (13) | 0.95 | |
Pregnancy energy intake (E0.5-E18.5) (kJ/day) | 37.6 ± 1.3 (7) | 49.1 ± 3.7 (7) | 0.02 | |
Plasma insulin E18.5 (ng/ml) | 0.36 ± 0.03 (7) | 0.58 ± 0.08 (10) | 0.04 | |
Plasma leptin E18.5 (ng/ml) | 5.85 ± 0.52 (7) | 6.61 ± 1.09 (10) | 0.54 |