Table 5. Renal function and renal morphology in adult offspring.
NFD Female | HFD Female | NFD Male | HFD Male | Pdiet | Psex | Pdiet*sex | |
---|---|---|---|---|---|---|---|
Renal function (t1/2), 6 months | 11.7 ± 0.6 | 12.3 ± 0.6 | 16.1 ± 0.6 | 16.2 ± 0.5 | 0.60 | <0.0001 | 0.70 |
Renal function (t1/2), 9 months | 11.7 ± 0.5 | 12.4 ± 0.5 | 15.2 ± 0.6 | 15.6 ± 0.5 | 0.33 | <0.0001 | 0.82 |
Albumin/creatinine ratio (μg/mg) | 6.0 ± 1.4 | 5.9 ± 1.3 | 7.2 ± 1.3 | 7.7 ± 1.3 | 0.89 | 0.25 | 0.84 |
Total glomerular volume, Vglom,kid (mm3) | 2.54 ± 0.21 | 2.31 ± 0.18 | 3.15 ± 0.22 | 2.87 ± 0.16 | 0.25 | 0.02 | 0.89 |
Kidney volume (mm3) | 97.1 ± 6.9 | 99.1 ± 6.1 | 139.4 ± 7.5 | 136.4 ± 5.5 | 0.94 | <0.0001 | 0.70 |
NFD n = 13–40 offspring from 8–11 litters, HFD n = 15–48 offspring from 12–15 litters.