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. 2016 Aug 22;11(8):e0161578. doi: 10.1371/journal.pone.0161578

Table 5. Renal function and renal morphology in adult offspring.

NFD Female HFD Female NFD Male HFD Male Pdiet Psex Pdiet*sex
Renal function (t1/2), 6 months 11.7 ± 0.6 12.3 ± 0.6 16.1 ± 0.6 16.2 ± 0.5 0.60 <0.0001 0.70
Renal function (t1/2), 9 months 11.7 ± 0.5 12.4 ± 0.5 15.2 ± 0.6 15.6 ± 0.5 0.33 <0.0001 0.82
Albumin/creatinine ratio (μg/mg) 6.0 ± 1.4 5.9 ± 1.3 7.2 ± 1.3 7.7 ± 1.3 0.89 0.25 0.84
Total glomerular volume, Vglom,kid (mm3) 2.54 ± 0.21 2.31 ± 0.18 3.15 ± 0.22 2.87 ± 0.16 0.25 0.02 0.89
Kidney volume (mm3) 97.1 ± 6.9 99.1 ± 6.1 139.4 ± 7.5 136.4 ± 5.5 0.94 <0.0001 0.70

NFD n = 13–40 offspring from 8–11 litters, HFD n = 15–48 offspring from 12–15 litters.