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. 2016 Aug 22;11(8):e0160732. doi: 10.1371/journal.pone.0160732

Table 2. Compliance of radiotherapy and surgical procedures according to different intervals.

< 6 wk 6–8 wk 8 wk p
n = 12 (%) n = 19 (%) n = 35 (%)
RT Toxicity 3 (25%) 2 (10.5%) 6 (17.1%)
Surgical procedure (n = 66) 0.59*
Sphincter saving 9 (75%) 14 (73.7%) 30 (85.7%)
LAR 9 (75%) 14 (73.7%) 25 (71.4%)
Transanal local resection / / 5 (14.3%)
Stoma operation 3 (25%) 5 (26.3%) 5 (14.3%)
Miles 2 (16.7%) 2 (10.5%) 4 (11.4%)
Hartmann 1 (8.3%) 3 (33.3%) 1 (2.8%)
R0 resection 12 (100%) 19 (100%) 34 (97.1%) > 0.99*
Postoperative complications 4 (33.3%) 7 (36.8%) 7 (20%) 0.10*
Clavien Dindo
grade I 1 4 4
grade II 1 1 1
grade III 1 (8.3%) 2 (22.2%) 2 (5.7%)
Distance from a.v. 0.37*
≤ 5 cm 7 (58.3) 9 (47.4) 13 (37.2)
5–8 cm 5 (41.7) 5 (26.3) 11 (31.4)
≥ 8 cm 0 (0) 5 (26.3) 11 (31.4)
Deaths 1 (8.3%) 1 (5.3%) 2 (5.7%)

*exact chi-square test