Table 3. Observed outcomes by interval to surgery.
| < 6 wk | 6–8 wk | 8 wk | p | |
|---|---|---|---|---|
| n = 12 (%) | n = 19 (%) | n = 35 (%) | ||
| TRG | 0.023^ | |||
| 1–2 | 2 (16.7) | 7 (36.8) | 19 (54.3) | |
| 3–5 | 10 (83.3) | 12 (63.2) | 16 (45.7) | |
| pT | 0.67^ | |||
| down stage | 9 (75.0) | 15 (78.9) | 29 (82.9) | |
| same or upstage | 3 (25.0) | 4 (21.1) | 6 (17.1) | |
| pN(**) | (***) | 0.31* | ||
| down stage | (§) | 1/5 (20.0) | 6/11 (54.5) | |
| same or upstage | (§) | 4/5 (80.0) | 5/11 (45.5) | |
| Stage | 0.87^ | |||
| down stage | 8 (66.7) | 10 (52.6) | 23 (62.9) | |
| same or upstage | 4 (33.3) | 9 (47.4) | 12 (37.1) |
^Exact Cochrane-Armitage trend test
(§) All patients were N0 at baseline
*by Fisher's exact test, group 6–8 wk vs group > 8 wk
**only patients with baseline N>0
*** two N1 patients received local excision