Table 1. Description of the 1152 non-AIDS defining events observed in 1227 patients who had at least four months in the follow-up.
APPROCO/ COPILOTE (ANRS CO8) cohort study 1997–2009.
| Non-AIDS defining events | n (%) |
|---|---|
| Bacterial infections | 241 (20.9) |
| Airway bacterial infections | 122 (10.5) |
| Upper airway bacterial infections | 7 (0.6) |
| Lower airway bacterial infections | 115 (10.0) |
| Intra-abdominal infections | 43 (3.7) |
| Skin and soft tissue infections | 17 (1.5) |
| Anal and perianal infections | 8 (0.7) |
| Bone and joint infections | 7 (0.6) |
| Bacteremia | 19 (1.7) |
| Urinary tract infections | 15 (1.3) |
| Other bacterial infections | 10 (0.9) |
| Cardiovascular events | 160 (13.9) |
| Ischemic events | 103(8.9) |
| Coronary events | 59 (5.1) |
| Arterial events | 28 (2.4) |
| Strokes | 12 (1.0) |
| Other ischemic events | 4 (0.4) |
| Non-ischemic events | 26 (2.3) |
| Vascular events | 36 (2.7) |
| Cancers | 116 (10.1) |
| Solid cancers | 103 (8.9) |
| Digestive cancers | 40 (3.5) |
| Oesophagus | 2 (0.2) |
| Stomach | 5 (0.4) |
| Hepatocellular carcinoma | 12 (1.0) |
| Pancreas | 5 (0.4) |
| Colon and rectum | 6 (0.5) |
| Anus | 6 (0.5) |
| Other digestive cancer | 4 (0.3) |
| Larynx and pharynx | 14 (1.2) |
| Bladder and urinary tract | 10 (0.9) |
| Lung | 12 (1.0) |
| Skin | 11 (1.0) |
| Other solid cancers | 16 (1.4) |
| Hodgkin lymphoma | 13 (1.1) |
| Digestives events | 97 (8.4) |
| Cirrhosis | 24 (2.1) |
| Pancreatitis | 17 (1.5) |
| Others | 56 (4.9) |
| Psychiatric events | 73 (6.3) |
| Depression with or without suicide attempt | 55 (4.8) |
| Other psychiatric disorders | 18 (1.6) |
| Neurological events | 56 (4.9) |
| Neurological events of central origin | 34 (3.0) |
| Peripheral neuropathy | 22 (1.9) |
| Kidney and urinary tract events | 68 (5.9) |
| Viral infections | 34 (3.0) |
| Varicella zoster infections | 15 (1.3) |
| Other viral infections | 19 (1.7) |
| Surgical diseases | 55 (4.8) |
| Skin diseases | 11 (1.0) |
| Endocrine diseases | 10 (0.9) |
| Gynecological diseases | 10 (0.9) |
| Hematological diseases | 18 (1.6) |
| Events in relation with drug addiction | 16 (1.4) |
| Ophtalmological diseases | 7 (0.6) |
| Lung events | 32 (2.8) |
| Rheumatological events | 33 (2.9) |
| Trauma | 40 (3.5) |
| General symptoms | 25 (2.1) |
| Hypersensitivity reactions not related to cART | 18 (1.6) |
| Deaths of unknown origin | 10 (0.9) |
| Other events (scabies, malaria…) | 22 (1.9) |