Average number of deleterious amino acid changes per barcode for each clinical outcome group for the STAD cancer set using PROVEAN (data compiled from the SOM files labeled, “SOM STAD, PROVEAN_new tumor_onco,” “SOM STAD, PROVEAN_new tumor_tumsupp,” “SOM STAD, PROVEAN_negandpos outcome_onco,” “SOM STAD, PROVEAN_neg and pos outcome_tumsupp”). The new tumor group represents 74 barcodes and the no-subsequent tumor group represents 224 barcodes. The negative outcome group represents 32 barcodes and the positive outcome group represents 71 barcodes.