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. 2016 Jul 8;4(3):e1208468. doi: 10.1080/21688370.2016.1208468

Table 3.

Correlation analysis for markers of intestinal permeability.

Parameters Ra P
ZO-1 mRNA (ileum) Occludin mRNA (ileum) 0.760 <0.001
ZO-1 mRNA (colon) Occludin mRNA (colon) 0.830 <0.001
ZO-1 protein (colon) Occludin protein (colon) 0.481 <0.001
ZO-1 mRNA (colon) Claudin-2 mRNA (colon) 0.803 <0.001
ZO-1 mRNA (ileum) Claudin-5 mRNA (ileum) 0.502 <0.001
ZO-1 mRNA (colon) Claudin-5 mRNA (colon) 0.588 <0.001
ZO-1 mRNA (ileum) JAM-A mRNA (ileum) 0.595 <0.001
ZO-1 protein (colon) Claudin-1 protein (colon) 0.739 <0.001
Claudin-1 mRNA (colon) JAM-A mRNA (colon) 0.887 <0.001
Claudin-1 mRNA (ileum) JAM-A mRNA (ileum) 0.507 <0.001
Occludin mRNA (ileum) JAM-A mRNA (ileum) 0.710 <0.001
Occludin mRNA (ileum) Claudin-5 mRNA (ileum) 0.546 <0.001
Occludin mRNA (colon) Claudin-2 mRNA (colon) 0.721 <0.001
Claudin-2 mRNA (colon) Claudin-5 mRNA (colon) 0.730 <0.001
Muc-2 mRNA (ileum) ZO-1 mRNA (ileum) 0.457 0.001
Muc-2 mRNA (ileum) JAM-A mRNA (ileum) 0.470 <0.001
Tff3 mRNA (ileum) Occludin mRNA (ileum) 0.547 <0.001
Tff3 mRNA (colon) Claudin-2 mRNA (colon) 0.551 <0.001
Defa-1 mRNA (colon) Claudin-5 mRNA (colon) 0.338 0.009
Defa-1 mRNA (ileum) Defa-4 mRNA (ileum) 0.707 <0.001
Defa-1 mRNA (colon) Defa-4 mRNA (colon) 0.564 <0.001
Defa-1 mRNA (colon) Muc-2 protein (colon) −0.455 0.001
Defa-4 mRNA (colon) Claudin-3 in urine −0.611 0.001
Defa-4 mRNA (ileum) Claudin-3 in urine −0.565 0.002
Defa-4 mRNA (ileum) iFABP-2 in plasma 0.557 0.002
iFABP-2 in plasma ZO-1 mRNA (colon) 0.427 0.017
iFABP-2 in plasma Claudin-1 protein (ileum) 0.549 0.002
iFABP-2 in plasma Claudin-2 mRNA (colon) 0.437 0.014
iFABP-2 in plasma Claudin-5 mRNA (colon) 0.496 0.006
iFABP-2 in plasma Mucus thickness (colon) −0.487 0.007
LPS in portal vein plasma Defa-1 mRNA (ileum) 0.483 0.002
LPS in portal vein plasma Defa-1 mRNA (colon) 0.417 0.006
LPS in portal vein plasma iFABP-2 in plasma 0.425 0.017
Lac/Man ratio (urine) Defa-1 mRNA (ileum) 0.379 0.004
Lac/Man ratio (urine) Defa-4 mRNA (ileum) 0.474 <0.001
Lac/Man ratio (urine) Defa-4 mRNA (colon) 0.499 <0.001
Lac/Man ratio (urine) Mucus thickness (ileum) −0,351 0.007
a

Spearman's rank correlation coefficient R; N = 42–48.