Figure 6. A model showing TFIIAγ5 as a key component of rice infection by Xanthomonas bacteria.
The bacteria hijack rice basal transcription factor TFIIAγ5 (IIAγ) by the transcription factor binding (TFB) region of their TALEs to induce host susceptibility (S) genes for infection. TS, amino-terminal translocation signal; RR, central repeat region; NLS, nuclear localization signal; AD, carboxyl-terminal transcription activation domain. The IIAγ belongs to the transcription pre-initiation complex. This complex consists of transcription factors IIA, which is composed of IIAβα subunit and IIAγ subunit, IIB, IID, IIE, IIF, and IIH, RNA polymerase II (Pol II), and TATA-binding protein (TBP). The binding of transcription pre-initiation complex to the TATA box of promoter was adopted and modified based on Yudkovsky et al. (2000).