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. Author manuscript; available in PMC: 2016 Sep 15.
Published in final edited form as: Mol Psychiatry. 2016 Mar 15;21(9):1232–1243. doi: 10.1038/mp.2016.15

Figure 4. Overexpression of DISC1 suppresses dendritic branching of MB neurons.

Figure 4

A. Dendrite branching patterns of wild-type and DISC1-expressing (DISC1OE) γ-neurons. Arrowheads indicate dendritic termini (claws), postsynaptic structures receiving inputs from olfactory projection neurons. Cells were labeled with a membrane-bound GFP (UAS-mCD8::GFP) driven by a MB GAL4-driver, OK107. Scale bar, 10 μm.

B, C. Quantification of dendritic phenotypes of DISC1 single-cell clones. B. Number of dendritic branch points. C. Number of dendritic claws. Partial claws were counted as 0.5. Single-cell clones were induced at an early larval stage and analyzed at young adult stage. *p < 0.05 and **p < 0.01 with one-way ANOVA and Dunnett’s post hoc test, n = 10 ~22.