Skip to main content
. Author manuscript; available in PMC: 2016 Sep 15.
Published in final edited form as: Mol Psychiatry. 2016 Mar 15;21(9):1232–1243. doi: 10.1038/mp.2016.15

Figure 6. DISC1 genetically interacts with dysbindin in the development of glutamatergic synapses.

Figure 6

A. Synaptic terminal branches of dysbe01028 heterozygous NMJs with DISC1 overexpression (DISC1OE). Green, motor neuron termini labeled with an anti-neuronal antibody (anti-HRP). Magenta, synaptic boutons labeled with anti-Synaptotagmin (SYT). Scale bar, 40 μm.

B–D. Quantification of NMJ synaptogenesis in w (CS10) control and dysb/+ backgrounds. B. Total synaptic bouton area. C. Number of synaptic boutons. D. Individual synaptic bouton size. E. Number of axonal branch points. *p < 0.05, **p < 0.01 and ***p<0.001 with t-test, n = 10.