Table 2.
Variable | Unadjusted | Adjusted | |||||||
---|---|---|---|---|---|---|---|---|---|
Model with Somatic Anxiety | Model with Affective Anxiety | ||||||||
Odds Ratio | 95% CI | P Value | Odds Ratio | 95% CI | P Value | Odds Ratio | 95% CI | P Value | |
Anxiety (Zung) | |||||||||
Total (mean) | 1.02 | 1.01–1.04 | 0.005 | ||||||
Somatic dimension (mean) | 1.91 | 1.36–2.67 | <0.001 | 3.13 | 2.16–4.53 | <0.001 | |||
Affective dimension (mean) | 1.03 | 0.82–1.30 | 0.780 | 1.19 | 0.96–1.48 | 0.117 | |||
Menopausal stage | <0.001 | <0.001 | <0.001 | ||||||
Premenopausal | Reference | ––– | –– | Reference | ––– | ––– | Reference | ___ | ___ |
Early transition | 2.54 | 1.82–3.54 | <0.001 | 1.89 | 1.32–2.73 | < 0.001 | 1.75 | 1.22–2.50 | 0.002 |
Late transition | 6.40 | 4.45–9.20 | <0.001 | 2.77 | 1.75–4.40 | <0.001 | 3.31 | 2.12–5.17 | <0.001 |
Early postmeno | 7.22 | 4.94–10.55 | <0.001 | 3.89 | 2.24–6.75 | <0.001 | 3.42 | 1.98–5.91 | <0.001 |
Late postmeno | 5.23 | 3.24–8.44 | <0.001 | 2.21 | 1.04–4.70 | 0.040 | 1.95 | 0.92–4.10 | 0.080 |
Age, current (y) | 1.11 | 1.09–1.14 | <0.001 | 1.10 | 1.05–1.15 | <0.001 | 1.09 | 1.04–1.14 | <0.001 |
History of depression3 | 1.62 | 1.14–2.29 | 0.007 | 1.36 | 0.90–2.05 | 0.145 | 1.60 | 1.06–2.42 | 0.023 |
log Estradiol, pg/mL1,2,3 | 0.84 | 0.80–0.90 | <0.001 | 0.96 | 0.90–1.03 | 0.236 | 0.96 | 0.90–1.02 | 0.162 |
log FSH, mIU/mL1,2,3 | 1.21 | 1.16–1.26 | <0.001 | 1.06 | 1.00–1.13 | 0.059 | 1.05 | 0.99–1.12 | 0.126 |
Education3 | |||||||||
>HS | 0.65 | 0.46–0.92 | 0.015 | 0.68 | 0.46–1.01 | 0.056 | 0.64 | 0.43–0.96 | 0.029 |
≤HS | Reference | ––– | ––– | Reference | ––– | ––– | Reference | ––– | ––– |
Current psychotropic medications | 2.82 | 1.97–4.04 | <0.001 | 0.41 | 1.29–2.95 | 0.002 | 2.02 | 1.34–3.07 | <0.001 |
BMI ≥ 30 | 1.51 | 1.15–1.98 | 0.003 | ||||||
Race | |||||||||
African American | 1.38 | 0.98–1.94 | 0.069 | ||||||
White | Reference | ––– | –– | ||||||
Alcohol < 1/wk | 0.76 | 0.56–1.03 | 0.076 | ||||||
Perceived stress (PSS) | 1.01 | 0.99–1.02 | 0.236 | ||||||
Employed vs not employed | 0.76 | 0.47–1.23 | 0.267 | ||||||
Current smoker | 0.97 | 0.69–1.38 | 0.885 |
. OR is for mean log hormone per 1 SD.
. Hormones were added separately to the models.
. Variables at P>0.05 were retained in the models for consistency between the 2 models.