Table 4.
Association of SNPs linked to XRCC6 and LASS1 with CKt in nonagenarian males
| Variable | rs132793 | rs2075762 | rs7252796 | ||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| b | se.b | p | b | se.b | p | b | se.b | p | |
| Cardiac | −9.5e-3 | 2.5e-3 | 8.0e-4 | −1.3e-2 | 2.7e-3 | 5.5e-5 | −1.5e-2 | 2.7e-3 | 9.1e-6 |
| eGFR | 1.1e-3 | 2.0e-4 | 5.9e-6 | 8.6e-4 | 2.5e-4 | 8.6e-4 | 1.3e-3 | 2.4e-4 | 1.6e-5 |
| EESI | 3.9e-6 | 1.0e-6 | 7.0e-4 | 3.0e-6 | 1.2e-6 | 1.8e-2 | 2.9e-6 | 1.2e-6 | 2.4e-2 |
| SNP | 2.4e-2 | 5.2e-3 | 8.4e-5 | 2.6e-2 | 8.6e-3 | 6.1e-3 | −2.8e-2 | 9.6e-3 | 6.9e-3 |
|
| |||||||||
| Model | df=25, R2=0.78, PF=1.1e-8 | df=25, R2=0.69, PF=5.8e-7 | df=24, R2=0.71, PF=5.8e-7 | ||||||
CKt = transformed creatine kinase; Cardiac = the number of heart-related problems in individual medical histories; EESI = Energy Expenditure Summary Index of the Yale Physical Activity Survey; eGFR = eGFR by the CKD-EPI equation; SNP = additive genotype model; Model = model statistics for each regression model; b = regression coefficient; se.b = standard error of b; df = degrees of freedom; R2 = adjusted R2; PF = p value from the F-test.