. Author manuscript; available in PMC: 2018 Mar 1.

Published in final edited form as: Lancet Diabetes Endocrinol. 2016 Feb 23;5(3):214–223. doi: 10.1016/S2213-8587(16)00034-6

Table 3.

Predictors of suppression and recovery of sperm output

	Slower Suppression	Less complete suppression	Faster recovery
Age	Older^*	-	Older^*
Race	Asian^*	Caucasian^*	Asian^*
BMI	-	Higher^*	-
Drug	No progestin Coadministration^*	No progestin coadministration^* Higher effective testosterone dose^*	Shorter acting testosterone formulation^*
Treatment duration	-	-	Shorter^*
Baseline sperm concentration	Higher^*	-	Higher^*
Baseline testosterone concentration	Higher^*	-	-
Baseline LH concentration	-	Lower^{^}	Lower^*
Other	-	Higher drug concentrations^{^} Higher insulin like 3^{^}	Faster initial suppression of sperm output^*

Factors from ^1,10

^{^}

Factors from ^54,55, requiring replication in larger studies