Table 1.

DNA-end resection proteins targeted by ubiquitin or SUMO E3 ligases.

DNA-end resection factor	E3 Ligase	Modification	Reference
Mre11/Rad50/Xrs2	global sumoylation response	SUMO	Cremona et al., 2012; Psakhye and Jentsch, 2012
NBS1	RNF8	Ubiquitin	Lu et al., 2012
	SCFSkp2	Ubiquitin	Wu et al., 2012
CtIP	BRCA1/BARD1	Ubiquitin	Yu et al., 2006
	CUL3KLHL15	Ubiquitin	Ferretti et al., 2016
	APC/CCdh1	Ubiquitin	Lafranchi et al., 2014
	RNF138	Ubiquitin	Schmidt et al., 2015
Sae2	Siz1/2	SUMO	Sarangi et al., 2015
BLM	RNF8 and RNF168	Ubiquitin	Tikoo et al., 2013
	MIB-1	Ubiquitin	Blackford et al., 2015; Wang et al., 2013
EXO1	PIAS1/4	SUMO	Bologna et al., 2015
	SCFCyclinF	Ubiquitin	Elia et al., 2015