Fig. 6.
Assessment of anti−tumour response in lung pseudo−metastatic tumour models. C57BL/6 mice (n = 6–8) were intravenously injected with 2.5 × 105 OVA−B16F10−Luc cells. On the 4th and 9th days post tumour cells injection, tumour−inoculated mice were immunized via footpad injection with the indicated treatments, each contained 6 μg OVA. (A) Lung pseudo−metastatic tumour model. Tumour growth was monitored by whole body imaging. Representative images for in vivo bioluminescent imaging and the corresponding post−mortem lung photographs are shown. (B) Quantification of photon flux, expressed as number of photons per second (p/s). Values are expressed as mean value ± SEM. (C) The weights of the lung excised from scarified tumour inoculated mice. Values are expressed as mean value ± S.D. *P < 0.05, **P < 0.01, ***P < 0.001.