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CSE knockout protected mice from VEGF induced hyperpermeability but did not alter basal permeability. Miles assay was performed on wildtype and CSE knockout mice. Tissue were collected after euthanasia, while Evans blue was extracted. A: Saline and VEGF were injected on the ear. * n=4, p<0.05. B: Evans blue was extracted from listed organs to determine basal permeability.
