Table 2.

Relationships between components of the E. antarcticum B7 fatty acid biosynthesis pathway following curation. The signals ⇒ and ⇔ indicate irreversible and reversible reactions, respectively.

Gene	Locus tag	EC number	Enzyme	Reaction	Fold change (log2⁡FC)
accA	Eab7_2059	6.4.1.2	Acetyl-CoA carboxylase carboxyl transferase alpha subunit	ATP + acetyl-CoA + HCO3 −⇒ ADP + orthophosphate + malonyl-CoA	0.4562
accB	Eab7_0870	6.4.1.2	Acetyl-CoA carboxylase biotin-carboxyl carrier protein	ATP + acetyl-CoA + HCO3 −⇒ ADP + orthophosphate + malonyl-CoA	−0.05773
accC	Eab7_0871	6.4.1.2 6.4.1.14	Acetyl-CoA carboxylase, biotin carboxylase subunit	ATP + acetyl-CoA + HCO3 −⇒ ADP + orthophosphate + malonyl-CoA	−0.5623
accD	Eab7_2060	6.4.1.2	Acetyl-CoA carboxylase carboxyl transferase beta subunit	ATP + acetyl-CoA + HCO3 −⇒ ADP + orthophosphate + malonyl-CoA	−0.2811
fabD	Eab7_1760	2.3.1.39	ACP S-malonyl transferase	Malonyl-CoA + ACP ⇔ CoA + malonyl-(acp)	0.9448
fabH1	Eab7_1911	2.3.1.180	3-Oxoacyl-ACP synthase III	Acetyl-CoA + malonyl-(acp) ⇔ acetoacetyl-(acp) + CoA + CO2	0.8512
fabF	Eab7_1910	2.3.1.179	3-Oxoacyl-ACP synthase II	Acetyl-(acp) + malonyl-(acp) ⇒ acetoacetyl-(acp) + CO2 + ACP	0.6942
fabG	Eab7_1895	1.1.1.100	3-Oxoacyl-ACP reductase	Acetoacetyl-(acp) + NADPH + H+  ⇔ (R)-3-hydroxybutanoyl-(acp) + NADP+	0.8523
fabZ	Eab7_2463	4.2.1.59	3-Hydroxyacyl-ACP dehydratase	(R)-3-hydroxybutanoyl-(acp) ⇔ but-2-enoyl-(acp) + H2O	0.12902
fabI	Eab7_1885	1.3.1.9 1.3.1.10	Enoyl-ACP reductase I	But-2-enoyl-(acp) + NADH + H+  ⇔ butyryl-(acp) + NAD+	0.2969
—	Eab7_2235	1.14.19.2	Acyl-ACP desaturase	Hexadecanoyl-(acp) + acceptor_reduced + O2  ⇒ hexadecenoyl-(acp) + acceptor + 2H2O	1.3768