Figure 6. Comparison of different feature extraction and classification methods on predicting benign versus malignant nodule when combined with existing models based on clinical and demographic information (left) Swensen et al.⁴ (right) McWilliams et al.⁵.

The bars are the median over 16 cross-validation splits, and the numbers are the p-value returned by a signtest to check if the median is above the vertical line. The vertical line represent performance using only the existing model without imaging information.