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. 2016 Aug 23;6:31852. doi: 10.1038/srep31852

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The best model for the prediction of 5-year overall survival consisted of 5 miRNAs (miR-200a, miR-200b, miR-200c, miR-429, miR-30a-3p) and 3 genes (C3orf52, CDH1, PAPSS2) (A,B). Independent validation of the integrated miRNA/mRNA EMT-signature by use of The Cancer Genome Atlas dataset KIRC (C). The predicted survival was assessed for the model without EMT-based miRNA/mRNA signature (D) and the model based only on the EMT-based miRNA/mRNA signature (age, gender, stage were fixed values) (E).