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. 2016 Aug 23;6:31701. doi: 10.1038/srep31701

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) Parental (P) SwissOF1-En1+/− females and C57Bl/6 males were intercrossed to obtain the F1 generation, from which En1+/− females and En1+/+ males were crossed to obtain F2-En1+/− and F2-En1+/+ male mice; (b) Genetic map of F2 population showing physical location of informative SNP markers; (c) Genotype frequency by F2 individual.