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. 2016 Aug 23;6:31763. doi: 10.1038/srep31763

Figure 6. The inhibition of TNFα in goose hepatocytes by lactic acid through HNF1α/C5 pathway.

Figure 6

(a) The expression of TNFα and HNF1α at mRNA level was suppressed in the livers of the overfed vs. normally fed geese. N = 6. (b) The expression of C5 and TNFα at protein level was suppressed in the livers of the overfed vs. normally fed geese. N = 4. (c) Ethanol induced TNFα expression was inhibited by lactic acid in goose primary hepatocytes. N = 4. (d) C5 expression was inhibited in goose primary hepatocytes transfected with siRNA targeting to HNF1α vs. negative control (NC) siRNA N = 4. *,**denote P < 0.05 and P < 0.05, respectively. Data in (a,c) and (d) are presented as the means ± SD.