Figure 2. Model’s output validation and calibration.

(A) 30-year model-generated cumulative incidence. (B) Vaccine- and natural disease-derived waning immunity fractions. (C) Vaccine coverage by dose (doses 1–7). Model-generated outputs depicted in (A), (B) and (C) are compared to 30-year cumulative incidence derived from surveillance data from two Alberta jurisdictions, waning immunity values described in the literature and dose-specific vaccine coverage derived from Canadian data sources respectively.