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. 2016 Aug 23;6:31844. doi: 10.1038/srep31844

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Sera samples obtained from the indicated groups of mice, just before the lethal challenge, were tested by ELISA for antibodies against M2e. Values represent the antibody titter of each individual mouse. The GMT was calculated for each group (solid lines). The dashed line depicts the antibody titer value of 39,000. All mice that elicited anti-M2e IgG titers above this threshold value survived the influenza virus lethal challenge.