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. 2016 Aug 23;6:31849. doi: 10.1038/srep31849

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Effects of chronic apelin treatment (Apelin) versus chronic aCSF treatment (Control) (a) on BAT Pgc1alpha mRNA expression; (b) on BAT Prdm16 mRNA expression; (c) on BAT UCP1 protein level; (d) on body temperature at room temperature and; (e) on body temperature at 4 °C. Experiments were performed with a set of 4–7 mice in each group. *p < 0.05, **p < 0.01.