Table 1. Study participants.
| Participants | N |
t(1;11) |
DSM-IV diagnoses (N) |
Medication |
|||
|---|---|---|---|---|---|---|---|
| Study | Y | N | Carriers | Non-carriers | Carriers | Non-carriers | |
| Linkage analysis | 107a | 37 | 69 | SCZ (2), SCZAFF (4), BP1 (2), rMDD (8), MDD (4), cyclothymia (3), conduct disorder (3), generalized anxiety (3), no psychiatric disorder (2), inadequate information (6) | rMDD (3), MDD (3), generalized anxiety (1), alcohol dependency (1), no psychiatric disorder (54), inadequate information (7) | NA | NA |
| Clinical assessment | 39 | 14 | 25 | SCZ (1), SCZAFF (1), BP1 (1), rMDD (3), MDD (3), cyclothymia (3), conduct disorder (1), no psychiatric disorder (1) | rMDD (2), MDD (1), generalized anxiety disorder (1) | Sodium valproate (3), +clozapine (1), +risperidone (1), +sertaline (1) | Amitriptyline (1) |
| Structural MRI | 30 | 12 | 18 | SCZ (1), schizoaffective (1), BP1 (1) rMDD (3), MDD (2), cyclothymia (3), conduct disorder (1) | rMDD (2), MDD (1) | Sodium valproate (3), +clozapine (1), +risperidone (1), +sertaline (1) | Amitriptyline (1) |
| MRS | 28 | 12 | 16 | SCZ (1), SCZAFF (1), BP1 (1) rMDD (3), MDD (2), cyclothymia (3), conduct disorder (1) | rMDD (2), MDD (1) | Sodium valproate (3), +clozapine (1), +risperidone (1), +sertaline (1) | Amitriptyline (1) |
| Functional MRI | 23 | 8 | 15 | rMDD (2), MDD (2), cyclothymia (3), conduct disorder (1) | MDD (1) | None | Amitriptyline (1) |
Abbreviations: BP1, bipolar 1; MDD, single episode depression; MRS, magnetic resonance spectroscopy; MRI, magnetic resonance imaging; NA, not available; rMDD, recurrent major depressive disorder; SCZ, schizophrenia, SCZAFF, schizoaffective disorder.
a
Translocation status was unavailable for one individual.