Figure 3.

Patient-derived cells expressed key components of the reelin pathway. (a) Representative western blot staining for reelin receptors apolipoprotein E receptor 2 (ApoER2), very low-density lipoprotein receptor (VLDLR), accessory protein Dab1, and phosphorylated Dab1 (phospho-Dab1). (b) Quantitation of reelin-binding receptors—ApoER2 and VLDLR in whole-cell lysates, normalized to β-tubulin. (c) Quantitation of Dab1 and phosphorylated Dab1 in whole-cell lysates, normalized to β-tubulin. For all graphs, control dataset was presented as black circles and patient dataset were gray squares. All data were presented as mean per group±s.e.m. Each point in the scatter plot represents data for each cell line used.