Table 1.

Previously reported antemortem diagnoses of PTTM

Year	Author	Primary site	Diagnostic method of PTTM	CT findings	PH	Treatment	Survival time
2007	Miyano et al. [5]	Stomach	VATS	Multiple tiny nodules	-	S-1 + dexamethasone + warfarin, aspirin	9 months
2008	Noguchi et al. [12]	Stomach	TBLB	Tiny nodules	+	No treatment	10 days
2008	Uruga et al. [8]	Lung	CT guided biopsy	Consolidation, ground glass attenuation	-	Carboplatin, paclitaxel	7 months
2011	Ishiguro et al. [2]	Unknown	TBLB	Mild interlobular septal thickening, ground glass opacities	+	CHOP(cyclophosphamide, doxorubicin, vincristine, prednisolone)	4 months
2011	Ueda et al. [7]	Esophagus	TBLB	Multiple bilateral diffuse interstitial infiltrative shadows	+	Fluorouracil, nedaplatin	9 days
2012	Kayatani et al. [3]	Unknown	VATS	Centrilobular ultrafine granular shadows	-	S-1, cisplatin	15 months
2013	Ogawa et al. [6]	Gastroduodenum	TBLB	A nodular shadow and septal thicken with a slight amount of pleural effusion	+	Bosentan, epoprostenol + imatinib + S-1, 5-fluorouracil	9 months
2013	Kitamura et al. [4]	Breast	TBLB	Ground glass opacities around the bronchovascular bundles	-	Irinotecan + warfarin	3 months
2014	Higo et al. [13]	Breast	Pulmonary wedge aspiration	Mosaic pattern	+	Bosentan, tadalafil + imatinib, bevacizumab + S-1	12 months
2015	Takahashi et al. (present case)	Breast	VATS	Peripheral consolidation in both lower lobes	-	Trastuzumab	32 months

PTTM Pulmonary tumor thrombotic microangiopathy, PH pulmonary hypertension, TBLB transbronchial lung biopsy, VATS Video-assisted thoracoscopic surgery, S-1 tegafur, gimeracil oteracil potassium