Table 3.
Site/Type of Test | Test costs per specimen $ (U.S) | Total specimens | Total tests cost (U.S. $) | Labor cost per specimen (U.S. $)¥ | Total labor cost (U.S. $)††† | Total cost (tests and labor cost) (U.S. $) | Total cost of HIV testing algorithm (tests and labor cost) (U.S. $) | Total cost per specimen (HIV-1 and HIV-2) (U.S. $) | Total positive specimens in HIV testing algorithm | Total cost per positive (HIV-1 and HIV-2) (U.S. $) | |
---|---|---|---|---|---|---|---|---|---|---|---|
Cost per test | Adjusted cost per test§ | ||||||||||
Massachusetts State Public Health Laboratory, Boston MA | |||||||||||
GS HIV Combo Ag/Ab EIA | 2.78 | 3.44 | 8438 | 29025.80†† | 3.36 | 28376.63 | 57402.44 | ||||
Multispot HIV-1/HIV-2 Rapid Test | 26.78 | 80.34 | 262 | 21049.08 | 24.44 | 6403.07 | 27452.15 | ||||
APTIMA HIV-1 RNA Qualitative Nucleic Acid Test (NAT) | 40.00 | 54.55 | 15 | 818.18 | 7.52 | 112.78 | 930.96 | ||||
85785.55 | 10.16 | 255 | 336.41 | ||||||||
| |||||||||||
Michigan State Public Health Laboratory, Lansing MI † | |||||||||||
GS HIV Combo Ag/Ab EIA | 3.50 | 4.46 | 6411 | 28609.09†† | 1.15 | 7388.11 | 35997.20 | ||||
Multispot HIV-1/HIV-2 Rapid Test | 25.70 | 35.98 | 170 | 6116.60 | 2.99 | 509.05 | 6625.65 | ||||
APTIMA HIV-1 RNA Qualitative Nucleic Acid Test (NAT) | 8 | 720.00 | - | 0 | 720.00 | ||||||
43342.85 | 6.76 | 165 | 262.68 | ||||||||
| |||||||||||
Maryland State Public Health Laboratory, Baltimore MD | |||||||||||
Architect HIV Ag/Ab Combo | 3.00 | 3.09 | 38334 | 118287.77†† | 0.55 | 21223.98 | 139511.75 | ||||
GS HIV-1 Western blot | 30.33 | 37.91 | 1034 | 39195.06 | 6.70 | 6931.42 | 46126.48 | ||||
Multispot HIV-1/HIV-2 Rapid Test | 23.52 | 33.60 | 574 | 19286.40 | 2.55 | 1462.17 | 20748.57 | ||||
SIV Western blot Assay (HIV-2 WB) Differential | 0 | 0 | 1 | 0 | 0 | 0 | 0 | ||||
HIV-1/HIV-2 proviral DNA PCR | 22.00 | 1 | 22.00 | 74.63 | 74.48 | 96.48 | |||||
LTR real time PCR (HIV-1 NAT) | 20.00 | 51 | 1020.00 | 15.90 | 811.19 | 1831.19 | |||||
Real time PCR gag (HIV-1 NAT) | 6.00 | 19 | 114.00 | 9.98 | 189.62 | 303.62 | |||||
Real time PCR pol (HIV-1 NAT) | 6.00 | 19 | 114.00 | 9.98 | 189.62 | 303.62 | |||||
bDNA (HIV-1 NAT) | 72.00 | 19 | 1368.00 | 1.12 | 21.33 | 1389.33 | |||||
210311.04 | 5.49 | 1003 | 209.68 |
Total kit cost plus cost of controls not provided in kit divided by number of tests not used as controls.
The product of labor hours per specimen and labor costs per hour.
In MI PHL, the estimated cost reimbursed to Florida PHL as part of a CDC/Association of Public Health Laboratories (APHL) NAT demonstration project was $90.
The numbers account for specimens that were run in duplicate when the initial test was reactive.
Labor cost per hour was determined by Bureau of Labor Statistics' estimate for the 2013 mean salary (including benefits). Labor hours per test were calculated either by being directly observed at the laboratory or from the estimates from literature.
-All costs are reported in 2013 US dollars