Table 1.
Basic characteristics of UCLEB participants with and without T2D
| Trait | No-T2D participants | T2D participants | p value | ||
|---|---|---|---|---|---|
| n | Trait | n | Trait | ||
| Age (years) | 13,015 | 61.1 (6.0) | 1803 | 61.3 (8.1) | 0.32 |
| Sex (percentage male) | 8068 | 62.00 | 1053 | 58.4 % | 0.003 |
| BMI (kg/m2) | 12,803 | 26.7 (4.3) | 1747 | 28.6 (5.80) | 1.346 × 10−36 |
| Triglycerides (mmol/l)a | 12,022 | 0.43 (0.55) | 1563 | 0.67 (0.75) | 8.461 × 10−33 |
| Total Cholesterol (mmol/l) | 12,736 | 6.28 (1.24) | 1784 | 6.04 (1.65) | 4.484 × 10−8 |
| HDL-cholesterol (mmol/l) | 12,493 | 1.42 (0.38) | 1757 | 1.25 (0.51) | 2.114 × 10−34 |
| LDL-cholesterol (mmol/l) | 12,385 | 4.00 (1.07) | 1607 | 3.62 (1.43) | 1.573 × 10−21 |
| Systolic blood pressure (mmHg) | 12,739 | 139.90 (22.80) | 1783 | 148.00 (30.60) | 1.650 × 10−23 |
| Diastolic blood pressure (mmHg) | 12,722 | 81.70 (12.90) | 1782 | 84.40 (17.30) | 3.716 × 10−9 |
| Fasting glucose (mmol/l)a | 12,741 | 1.69 (0.15) | 1670 | 1.98 (0.19) | 2.54 × 10−303 |
| Insulin (µIU/ml)a | 7732 | 1.89 (0.62) | 456 | 2.50 (0.66) | 1.686 × 10−80 |
| Glycated haemoglobin (%) | 8711 | 5.37 (0.65) | 1807 | 6.80 (0.98) | 8.14 × 10−265 |
Mean and standard deviation of each trait (where applicable) is shown in those with and without T2D. Results were adjusted for age and sex
aVariables were log transformed