Table 2.
Overall performance characteristics
| Alert | Cutoff | sens | fpr | auc | spec | ppv | npv | FP/Day | Inc. Sepsis TP | |
|---|---|---|---|---|---|---|---|---|---|---|
| Nurse | Other | |||||||||
| Triangle Nurse | 1.000 | 54.3 % | 3.1 % | 0.756 | 96.9 % | 6.1 % | 99.8 % | 6.44 | ||
| SIRS Derived | 1.000 | 21.6 % | 0.4 % | 0.606 | 99.6 % | 17.2 % | 99.7 % | 0.80 | 187 | 4 |
| Cut05 | 0.050 | 76.4 % | 4.7 % | 0.859 | 95.3 % | 5.8 % | 99.9 % | 9.64 | 22 | 100 |
| Cut04 | 0.040 | 79.0 % | 5.4 % | 0.868 | 94.6 % | 5.2 % | 99.9 % | 11.16 | 18 | 105 |
| Sens80 | 0.036 | 80.1 % | 5.8 % | 0.871 | 94.2 % | 4.9 % | 99.9 % | 12.03 | 17 | 108 |
| FPC15 | 0.026 | 85.2 % | 7.3 % | 0.890 | 92.7 % | 4.2 % | 99.9 % | 15.00 | 13 | 122 |
| MaxAUC | 0.017 | 89.2 % | 9.9 % | 0.897 | 90.1 % | 3.3 % | 100.0 % | 20.33 % | 12 | 135 |
| NrsFP | 0.097 | 70.2 % | 3.1 % | 0.835 | 96.9 % | 7.8 % | 99.9 % | 6.44 | 32 | 88 |
| NrsSens | 0.330 | 54.3 % | 1.6 % | 0.763 | 98.4 % | 11.4 % | 99.8 % | 3.27 | 64 | 64 |
SIRS systemic inflammatory response syndrome, Cut05/Cut04 Bayesian cutpoint threshold of 0.05/0.04, Sens80 threshold for sensitivity = 80 %, FPC15 threshold of 15 false positive alerts per day, MaxAUC threshold maximizing area under the receiver operating characteristic curve, NrsFP nurse-driven false positive threshold, NrsSens nurse-driven sensitivity threshold. Boldface indicates the primary cutpoint used