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. 2016 Aug 22;16(1):668. doi: 10.1186/s12885-016-2677-3

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Case selection and flow diagram for molecular testing of ampullary adenocarcinoma. Seventy-nine cases of ampullary adenocarcinoma were identified for this study. Tumor specimens were assigned a reference histological subtype (intestinal or pancreaticobiliary) by a gastrointestinal pathologist. The comparator cohort comprised 54 cases to measure the prognostic performance of the 3 classifiers: 92-gene classifier, histological subtype, and histomolecular phenotype