Table. Characteristics of 9 mcr-1–positive Escherichia coli isolates from companion animals and human patients, Guangzhou, China.

Characteristic	Isolate
	PET01	PET02	PET03	PET04	PET05	PET06	EC07	EC08	EC09
Isolation date	2016 Jan 1	2016 Jan 1	2016 Jan 2	2016 Jan 2	2016 Jan 2	2016 Jan 4	2015 Oct 10	2015 Nov 2	2015 Nov 21
Specimen source	Cat	Dog	Dog	Dog	Cat	Dog	Human	Human	Human
Specimen type	Feces	Feces	Feces	Feces	Feces	Feces	Urine	Urine	Blood
Phylogenetic group	B2	D	D	D	B2	D	D	B1	B1
ST†	ST93	ST354	ST354	ST354	New	ST354	ST354	ST156	ST156
PFGE type	IV	I	I	I	V	I	I	II	III
Resistance genes	mcr-1, blaTEM-1, qepA	mcr-1, blaTEM-1, blaCTX-M-15, fosA3, aac(6′)-Ib-cr	mcr-1, blaTEM-1, blaCTX-M-15, fosA3, aac(6′)-Ib-cr	mcr-1, blaTEM-1, blaCTX-M-15, fosA3, aac(6′)-Ib-cr	mcr-1, blaTEM-1, blaSHV-12, blaCTX-M-15, fosA3, rmtB, qnrS, aac(6′)-Ib-cr	mcr-1, blaTEM-1, blaCTX-M-15, fosA3, aac(6′)-Ib-cr	mcr-1, blaTEM-1, blaCTX-M-15, fosA3, aac(6′)-Ib-cr	mcr-1, blaTEM-1, blaCTX-M-55, fosA3, rmtB, qepA1	mcr-1, blaIMP-4, blaTEM-1, blaCTX-M-55, fosA3, rmtB, qepA1
MIC, μg/mL
Colistin	16	8	8	16	16	8	8	8	64
Polymyxin B	16	16	16	32	16	16	8	8	64
Ampicillin	>256	>256	>256	>256	>256	>256	>256	>256	>256
AMX/CLV	16	32	32	32	256	16	32	16	16
Cefotaxime	64	>256	256	>256	256	>256	256	256	>256
Ceftazidime	16	256	128	256	64	256	128	32	>256
Cefepime	8	256	128	256	16	256	64	64	>256
Gentamicin	128	>256	>256	>256	256	>256	>256	>256	>256
Amikacin	4	>256	>256	>256	>256	>256	>256	>256	>256
Ertapenem	<0.25	1	0.5	0.25	<0.25	1	0.5	<0.25	>16
Imipenem	<0.25	<0.25	<0.25	<0.25	<0.25	<0.25	<0.25	<0.25	>16
Meropenem	<0.25	<0.25	<0.25	<0.25	<0.25	<0.25	<0.25	<0.25	>16
Fosfomycin	32	>512	>512	>512	>512	>512	>512	>512	>512
Tigecycline	<2	<2	<2	<2	<2	<2	<2	<2	4
Nitrofurantoin	<16	32	32	32	128	32	64	64	32
Ciprofloxacin	256	128	128	128	64	128	128	256	256

*AMX/CLV, amoxicillin clavulanic acid; PFGE, pulsed-field gel electrophoresis; ST, sequence type.
†By multilocus sequence typing.