Table 3. Predictors of favorable outcome among patients initiating treatment for extensively drug-resistant tuberculosis, KwaZulu-Natal and Eastern Cape Provinces, South Africa, 2006–2010*.
| Predictor | Unadjusted analysis |
Multivariate analysis |
|||
|---|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | ||
| HIV positive | 1.08 (0.59–1.98) | 0.81 | 1.29 (0.60–2.75) | 0.52 | |
| Previous MDR TB treatment | 0.59 (0.33–1.06) | 0.08 | 0.77 (0.35–1.66) | 0.50 | |
| Smear negative | 2.97 (1.41–6.26) | 0.004 | 2.69 (1.29–5.63) | 0.009 | |
| Age | 0.99 (0.97–1.02) | 0.55 | 0.99 (0.96–1.02) | 0.58 | |
| Weight >50 kg | 1.93 (0.93–4.02) | 0.08 | 3.64 (1.68–7.92) | 0.001 | |
| KwaZulu Province | 1.98 (1.12–3.52) | 0.02 | 1.69 (0.81–3.53) | 0.16 | |
| Male sex | 0.57 (0.30–1.09) | 0.09 | 0.77 (0.36–1.67) | 0.51 | |
| Cavitary disease by chest radiograph | 0.61 (0.33–1.10) | 0.10 | 0.50 (0.24–1.03) | 0.06 | |
*p values in bold are statistically significant. HR, hazard ratio; MDR TB, multidrug-resistant tuberculosis.