The OJC-associated lineage of multidrug-resistant Shigella
sonnei in context with other global lineages. These background
(non-OJC) isolates were contemporaneously collected and selected on the basis of
phage typing; that is, including diverse phage types, but focused on representing
phage types associated with OJC outbreaks. The midpoint rooted maximum-likelihood
phylogenetic tree shows the relationships of 437 sequences from study of travel-
and community-based transmission of multidrug-resistant S.
sonnei among international OJCs compared with 118 isolates from a
global context database of previously defined lineages of S.
sonnei. Lineages are labeled along branches. Adjacent tracks are
colored according to the inlaid key and show epidemiologic features of the isolate
(lane 1, sample designation; lane 2, country; lane 3, year of isolation). Year of
isolation is colored on a continuous heat map scale for 1992–2014, shown by
hash symbols (#). Scale bar indicates single-nucleotide polymorphisms. OJCs,
Orthodox Jewish communities.