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. 2016 Aug 23;16(1):28. doi: 10.1186/s12861-016-0128-7

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — The ciliated Left-Right Organizer: a synapomorphy of the deuterostomes. a–c Schematic drawings of sea urchin (a), amphioxus (b) and Xenopus (c) gastrula/neurula stage embryos (anterior to the left). In all cases the archenteron harbors cells of mesodermal fate (SM, red), which in frog and sea urchin are ciliated and function as LROs. The position of mesodermal LROs is indicated by an arrowhead. d nodal is evolutionary conserved among metazoans except for the ecdysozoa. Deuterostomes share a ciliated LRO as a common synapomorphy. Drawings adapted in parts from Blum et al. 2014 [3]