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. 2016 Aug 22;15(1):146. doi: 10.1186/s12934-016-0547-y

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Effect of rapamycin treatment on cell growth and PMA biosynthesis. a Growth on PDA plate; b Shake flask fermentation; c Transcription levels of genes in the PMA and TOR pathways. Yield (Yp/x): the ratio of PMA to cell biomass concentration (g/g). Data are given as the average of triplicate experiments