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. 2016 Jul;11(7):1128–1133. doi: 10.4103/1673-5374.187049

Figure 4.

Figure 4

Apelin-13 reduces TBI-induced cell apoptosis in the brain 48 hours after TBI.

Arrows show normal cells and arrowheads point to TUNEL-positive cells in the sham (A), TBI (B), and apelin-13 (C) groups. Scale bars: 50 μm. (D) Quantification of TUNEL-positive cells in the injured cortex (in 400-fold fields). Data are presented as the mean ± SEM (6 mice in each group), and were analyzed by the rank-sum test. **P < 0.01, vs. TBI group; ##P < 0.01, vs. sham group. TBI: Traumatic brain injury; TUNEL: terminal deoxyribonucleotidyl transferase (TDT)-mediated dUTP-digoxigenin nick end labeling.